Carcinogens, Mutagens and Reprotoxic chemicals

CMRs are substances that are carcinogenic, mutagenic, or toxic to reproduction. In other words, they have inherent properties that can cause cancer, alter DNA or damage reproductive systems. These properties correspond to article 57 a-c of REACH.

To identify CMRs, the EU Regulation on Classification, Labelling and Packaging (CLP, EC 1272/2008) has been used as a source. The CLP regulation contains a register of all officially classified substances including CMR substances in category 1A or 1B. These substances are recognised under REACH as by default meeting the criteria of SVHCs (according to article 57 a, b and c).

To remove substances that are not within the scope of REACH regulation, or that have unclear identity, the following measures were taken:

  • From the above-mentioned register, pesticides having a standardised name assigned by the International Organization for Standardization (ISO) have not been included in the SIN List if not registered with a full REACH registration dossier.
  • Entries in the above-mentioned register referring to mixtures where one of the substances is a CMR and is present in the mixture in concentrations above 0.1% have not been included in the SIN List either (unless they have first been added to the Candidate List).
  • Entries lacking CAS numbers and EC numbers are not included, since they do not identify a unique substance or a unique substance group (unless they have first been added to the Candidate List).

For each SIN List update, chemicals that have been newly classified as CMR 1a and 1b in the interim have been added.